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How MLB Betting Odds Are Set, and What the Moneyline Really Tells You


By Connie Etemadi

Published on September 08, 2025

From the outset, sports betting appears to be pure luck-based gambling. Yet, its ever-growing popularity online and in the public imagination implies there is more to it. After all, how could bettors be winning big if they didn’t have a winning strategy handy?

Fortunately, in the information age, formulating these strategies only requires a little bit of research from reliable sources. Online sportsbooks make it easier than ever to understand the MLB odds for betting and winning. Starting with understanding the moneyline, researching these various factors can help give bettors a competitive edge for winning big.

Setting the Line: How Sportsbooks Determine MLB Odds

Simply put, sportsbooks can quickly crunch the numbers using powerful algorithms, historical data, and expert oddsmakers to help establish opening lines. Early odds are adjusted based on current injuries for players and ongoing lineup announcements.

Sportsbooks also consider weather conditions for players, considering both their typical practice conditions and the weather trends for where games are to be played.

Lastly, early odds are adjusted based on current trends in public betting behavior. Bettors can review these up-to-the-minute data points online, keeping the latest and greatest data on MLB odds well in mind while they place their bets.

Decoding the Moneyline for the MLB Odds

Understanding the moneyline doesn’t need to be complicated. A relatively straightforward form of betting, favorites are associated with unfavorable odds, whereas underdogs are more likely to garner favorable odds. For example, if betting $140 on a favorite, the potential payout is lower, with an estimated amount of around $100. Conversely, betting on the underdog is associated with a higher potential payout, with favorable odds suggesting an estimated $120 payout after a $100 bet.

In comparison, run line bets will have additional speculative elements, including score predictions and figuring in handicaps. A totals bet looks at the combined final score and wagers on whether that score is more or less than the number guessed by the sportsbook. These types of bets can offer additional ways to win, but are less straightforward than moneyline betting.

What the Moneyline Really Reflects for MLB Odds

The moneyline helps paint a comprehensive picture of a team’s capabilities, which is a valuable metric for determining MLB odds. Not simply limited to examining a team’s strength and performance, the moneyline reflects how pitching matchups might play out and the overall bullpen depth.

The moneyline looks at a team’s recent performance for betting odds. It also considers overall public sentiment and the current betting volume. For example, while the Yankees might be calculated at -170 due to heavy fan bets, they may not be the team actually dominating on the diamond.

Betting Against the MLB Odds: Value and Overreaction

Considering that fan favorites may not actually predict real wins, bettors will do well to look at where media hype or marquee teams might inflate odds. Bettors may choose a more contrarian approach to their bets, enacting a “fade the public” strategy when making decisions.

Bettors can select “value bets,” placing their money where odds may not reflect the actual win probability due to a lack of popularity or public disinterest. Or as MLB betting strategist Kim Rhodes puts it, “[o]dds don’t just tell you who’s expected to win; they reveal how the public is thinking. Smart bettors read between the lines.”

When the Public Gets the MLB Odds Wrong

Public perception can, at times, be blinded by the pinstripes: overfocusing on the storied Yankees or stuck singing along at Fenway while losing sight of the facts in front of them. A recent example of this possibility is the Pirates-Dodgers matchup in the spring of 2025, which ended in an upset.

The Pirates won an impressive 3-0 victory, to the surprise of many, including seasoned sports bettors. Even so, more savvy bettors recognized the Pirates as an undervalued underdog and placed their bets accordingly. While a strategy is never a guarantee, understanding these factors can make for a better bettor and bigger potential payouts.

FAQ

Q: Why do MLB moneylines shift before game time?

A: Odds shift due to betting volume, new injury updates, or changes in starting pitchers.

Q: How accurate are moneyline odds in predicting winners?

A: They’re generally accurate over time, but short-term value plays can create profitable upsets.

Q: Can you make a living betting MLB moneylines?

A: It’s difficult. While some bettors find long-term success, most use it for recreation and strategy testing.

Newsdesk Editor